Bradley Cooper, a main character in the first two installments of what will now be the Hangover trilogy, appeared on the Graham Norton Show in England to promote the series’ second film. During his appearance, he mentioned the production of a third film, saying “I personally want to do it. I hope we’re going to start shooting in September. I know Todd Phillips is working on the script.”

Apparently, the next addition won’t follow the same pattern the first two did. Cooper said “We adhered to the formula in the second one, for those of you who’ve seen it, and the third one, which would close the whole sort of trilogy, which now it would be a trilogy — even though we thought we would never make a second one, let alone anybody see the first one — I think it will take place in Los Angeles and maybe not adhere to the structure. It might be different”.

The second Hangover film earned $581 million worldwide, ranking as the highest-grossing comedy of all time.

Todd Phillips confirmed with MTV today that a “Hangover” sequel was completely in the works, slated to hit the big screen in 2010.

Warner Bros. had been in talks for the sequel before “The Hangover” even hit theaters last week, showing its faith the film would be the box office success it turned out to be.

When Blast had a chance to speak with “The Hangover” star Ed Helms, he had not been under the impression a sequel was as set as it now is. He told Blast the talks were to get ahead of the game so they were not faced with waiting too long to get a sequel in the works like they did with “Old School:” a sequel that recently popped up on IMDB after the successful opening weekend of “The Hangover.” Sounds like Warner Bros. has some big plans for their hit R-rated comedies.

Phillips confirmed that his four leading men: Helms, Bradley Cooper, Zach Galifianakis and Justin Bartha would all be returning for “The Hangover” sequel. So what exactly will the sequel be about? With the film still a year away, nothing can be certain, but we like Helms’ suggestion best:

“The only way to heighten “The Hangover” I think, is to take it outer space. So yeah, I think it would be a bachelor party in a space station.”

That is definitely something we would pay to see.

While everyone’s focus on Warner Bros. summer releases was settled on “Terminator Salvation” and “Harry Potter and the Half-Blood Prince,” they were busy sneaking in a summer comedy of epic proportions. Starring Bradley Cooper, Ed Helms and Zach Galifianakis, “The Hangover” follows three groomsmen who lose the groom in Vegas the night of his bachelor party and have to find him by figuring out what exactly happened the night before in order to get him back in time for his wedding. But instead of leaving the hilarity at that, director Todd Phillips (“Old School”) included a tiger, Heather Graham as a hooker and Mike Tyson.

The true gem of the film is stand up comedian Zach Galifianakis. Best known for “Live at the Purple Onion” and his Absolut Vodka shorts on the “Tim and Eric Awesome Show,” Galifianakis stole every scene he was in, whether it was wearing the most un-Vegas outfit available or carrying a baby around on his chest. Galifianakis’ pitch-perfect comedic timing took the film to a new level of hilarity that it couldn’t have reached before.

But it is the chemistry between Cooper, Helms and Galifianakis that truly makes the film more than just a “bros have a crazy night in Vegas” comedy. For three actors from completely different ends of the comedy spectrum “" Cooper from “Yes Man,” Helms from “The Office” and Galifianakis from his stand up “" they work perfectly well together in their roles. There are poignant moments between the three leads as the film progresses that show, not just tell, that a bond has developed between the three men, especially between Cooper and Helms with Galifianakis. Galifianakis’ character of Alan “" the soon-to-be brother-in-law of groom Doug (Justin Bartha) “" was the awkward member of the group from the beginning who clearly didn’t belong, and whom Doug’s best friends Phil and Stu (Cooper and Helms) weren’t especially big fans of coming on their Vegas adventure. But by the end of the film, a real friendship develops in a subtle way that is rare to see on the big screen.

From the creators of “Old School,” this film has been pegged as a follow-up to the 2003 Will Ferrell classic. “The Hangover” is not only a follow-up “" it’s better. Taking the hilarious adventures to an entirely new level (you thought you knew the tiger would be hilarious from the trailers, but just wait), the film still manages to feel relate-able at its core. A story of three people becoming friends, of learning to stand up for what’s best for your happiness and of the true measure of responsibility is something all viewers can relate to.

While Phil, Stu and Alan’s adventures trying to find the missing Doug take up the bulk of the film’s 100 minutes of running time, an extra 20 to 30 minutes of added hilarity would have been for the film’s benefit. Advertisements for “The Hangover” made it clear that Phil, Stu and Alan did insane, ridiculous things while they were drunk, but by the time the ending credits started rolling, there was a sense of “that’s it?” To be clear, insane, ridiculous things did happen, but the film left telling the specifics of what exactly happened the night before (if you can write a timeline of exactly what happened, when, during that night after the first viewing, get back to me) to telling of the male bonding experience that occurred.

Without a doubt, go see “The Hangover.” In a summer of blockbuster comedies, “The Hangover” is shaping up to be the best one out there. If you have been itching for a sequel to “Old School” “" or just itching for something that will make your sides hurt from laughing too hard “" go see this movie.

“The Hangover” hits theaters this Friday, but Blast was lucky enough to catch up with Ed Helms when he was in Boston and get the inside scoop on what it was like working with a live tiger, the bromance that developed on set and news on a possible “Hangover” sequel. Some spoilers are revealed in the interview.

BLAST: Between you, Bradley Cooper and Zach Galifianakis, you all come from really different comedy backgrounds. How was it working together?

ED HELMS: Well, you just kind of hit on it. I think that we’re all so different that there was no competition because like everyone’s funny in a very different way, so a line that Zach might say that’s really funny would never work for me or my character. So there was never a sense of competitiveness about like trying to one-up each other. To the contrary, we all just sort of dovetailed really nicely and actually, I think as people we’re really different too, and that just made for a really easy dynamic hanging out. As the characters become friends over the course of the movie, the three of us really like “" after spending 14 hours a day together for three months “" got really tight. And I think you see that. I mean, you actually see that on film, hopefully. I mean I see it when I watch it now, it’s like, you sort of feel like how easy it became between us.

BLAST: Usually with the character of Alan (Zach Galifianakis), that kind of outsider-from-the-group character, that is usually enforced a lot in these movies, but in this one it really subtly showed your friendship. Like he asks at the end, “Does this look like Phil’s (Bradley Cooper’s) hair?” and you’re like “Oh yeah, it’s totally Phil’s haircut.”

EH: Thank you for saying that. That’s so funny. The whole thing where Alan has a bro-crush on Phil, that was invented by Zach on set, and it sort of just kept bubbling up and it became this hilarious thing. So that little exchange, when we’re getting hair and makeup for the wedding scene, Zach was like, “I think I should have Phil’s hair.” And it was really such a funny moment. So then that little exchange became a moment, so it was like, “What happens there?” Well Zach will ask if his hair looks good like Phil’s and, initially, [director] Todd [Phillips] was like, “Yeah, you dismiss him, or you know, tell him he’s an idiot or whatever” and I was like, “No, that’s not where we’re at anymore.”

BLAST: So did that [scene] come from you?

EH: Yeah, that’s why I was really psyched you brought it up, because like, I felt strongly that at that point in the movie we all have each others’ back, and even this ridiculous thing like Alan trying to look like Phil, I’m suddenly on board with. And there’s a lot of moments that I really pushed for in the movie that, and I’ll say this, working with Todd is so great because he’s so collaborative and I trusted him on 99 percent of the comedic choices in the movie, but the one thing I kept pushing was that we don’t shy away from actually like having, not poignant, but genuine affection between these guys. Another good example is when, and this is before we really become friends, but like when Zach has that horribly degenerate moment with the baby, and I laugh at it. My character laughs at it, which wasn’t in the initial cut. And it’s like, come on, let them have this moment, because it is funny. It’s like, let’s lay a little groundwork of they do crack each other up. And then later on when Mr. Chow’s goons are beating us up and one of them says, “Yeah, you thought he was a lucky charm so you put him in the trunk” and Phil and I share a laugh, and that once again wasn’t in the initial cut and it was like, when two people laugh at something, it’s a shared moment, and it’s just groundwork for this growing friendship, and I just love all those moments. They’re so small but they like just make it.

BLAST: I actually think that is one of the better aspects of the movie, that it’s not just your average go crazy moment. But speaking of going a little crazy, which were you more worried about working with: the tiger, or Mike Tyson?

EH: The tiger. I was pretty sure Mike Tyson would be cool, and it turns out he’s even cooler than I thought. The tiger, however, doesn’t take direction very well and likes to eat people.

BLAST: The scene with you in the bathroom: was that the live tiger, or was that CGI?

EH: It’s both. It’s funny, we were shooting the DVD commentary and this scene came up, and I was like, “In this scene “"” and Zack like [stopped me from talking]. I think you can see it because the DVD commentary is actually video, so I think you can see Zach being like, “Shh.” So I didn’t say it on the DVD but I’ll tell you, I did a ton of takes before I walked in and threw the steak to the actual tiger. I think that what you see in the final cut is a combination of one of those takes with a composited thing of me coming in, getting scared, and running out. The getting scared I didn’t do with the real tiger. And then the tiger actually lunging and pawing, that was done with a trainer. So those two pieces were composited together. But it looks incredible. That said, and I don’t want to undersell the extreme valor and bravery I exhibited in shooting those scenes because”¦ Actually, none of it was brave or valorous. I was terrified the entire time. But we were so damn close to that tiger for a ton of stuff, particularly, way more scary than that stuff in the bathroom, was the stuff in Tyson’s yard, during the flashback, when you’re seeing the video footage of us just traipsing around a yard with the fucking tiger, I mean that was [terrifying].

BLAST: Before this movie even came out, it must have been about a month ago, they okayed a “Hangover 2″ for 2011. Do you know anything about that?

EH: Well, Warner Bros. clearly likes this movie a lot, which is very exciting because that’s why I’m talking to you now. They’ve like put tons of energy behind promoting this movie, which is very exciting. That said, they haven’t greenlit a movie yet. I think they’re, and I’m not in the loop so much, it seems that they’re just kind of like exploring the possibility and maybe even tossing around ideas for it. At the end of the day, this movie has to perform before they’ll greenlight a sequel. I think they just wanted to get ahead of the game. “Old School” I think, was a movie that they immediately wished they had sort of gotten ahead of on putting a sequel together, and it didn’t happen. But, you know, it would be so fun. This was the most fun thing to do in the history of the universe, so if we get to do another one.

BLAST: What do you think it will be about?

EH: The only way to heighten “The Hangover” I think, is to take it outer space. So yeah, I think it would be a bachelor party in a space station.

BLAST: But who would be getting married?

EH: Maybe me and Heather. Who knows.

BLAST: Maybe Zach and that baby.

EH: [laughs] That’s fucked up.

BLAST: How was the baby during shoots? Did you have to make it miserable to cry during shooting?

EH: Here’s the thing: babies cry all the time. The baby made us miserable. We used I think like eight babies. Six or eight babies. Six. Gosh, I can’t even remember now. I want to say eight. There were a couple that we used a lot because they were actually so wonderful, but if you see the movie, there’s actually like three or four different babies. Sometimes they change in the middle of the scene. Because they start crying and you have to switch them out. And Todd was so funny, he was like, “No one cares. They all look the same.”

BLAST: It’s funny because Zach actually came and performed at Northeastern University a couple months ago and the promo shot for it was actually him holding the baby. Speaking of Zach, is he as awkward in real life as he can portray himself in his stand-up?

EH: No. No, thankfully. I mean, he’s goofy and incredibly silly and that sensibility is just very much a part of who he is, but he’s also just extremely kind and sweet and I love Zach so much because he just loves to giggle. We kept shutting down the set because we’d keep getting in these giggle fits. It’s totally ridiculous. I think he just makes me laugh, and then when I laugh he laughs, and it’s just this horrible feedback loop, and Todd gets mad, and that just makes it even harder to stop laughing.